Cutis verticis gyrata in a neonate

Area of Science:

• Dermatology
• Neonatology
• Genetics

Background:

• Cutis verticis gyrata (CVG) is a rare condition characterized by skin folds on the scalp.
• It is classified into primary and secondary forms based on the absence or presence of underlying neurological or systemic disorders.
• Primary CVG is typically idiopathic, while secondary CVG is associated with various genetic syndromes and conditions.

Observation:

• This report details the first documented case of primary cutis verticis gyrata in a neonate.
• The infant presented with other congenital anomalies.
• Histologically normal skin biopsy from the lesion was observed.

Findings:

• The diagnosis was supported by a normal skin biopsy and the presence of neurological deficits.
• Follow-up at seven months revealed persistent hypotonia and significant developmental delay.
• This case highlights a potential association between primary CVG and neurodevelopmental issues in neonates.

Implications:

• This case expands the understanding of primary cutis verticis gyrata presentation in neonates.
• It underscores the importance of thorough evaluation for associated congenital anomalies and neurological deficits.
• Further research is needed to elucidate the etiology and long-term prognosis of primary CVG in infants.