[Immunoelectrophoretic analysis of reactions between heparin and pregnancy proteins]

A procedure is described for study of reactions between heparin and human blood serum proteins using zonal electrophoresis in agar gel containing various amounts of heparin. The alterations occurring were registered by means of cross immunoelectrophoresis. A shape of the pregnancy protein precipitates and their electrophoretic mobility were altered depending on concentration of the glycosaminoglycan present. Characteristic properties of reactions between heparin and pregnancy proteins are discussed as well as the perspectives of the use of this method for study of proteins reacting with heparin.