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Psoriasis provoked by beta-blocking agents.

N Arntzen, G Kavli, G Volden

    Acta Dermato-Venereologica
    |January 1, 1984
    PubMed
    Summary
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    Beta-blocking agents may provoke psoriasis in patients. Seven of 23 patients developed psoriasis after starting these drugs, with a significantly later age of onset. Stopping medication led to remission in most cases.

    Area of Science:

    • Dermatology
    • Pharmacology

    Background:

    • Psoriasis is a chronic inflammatory skin condition.
    • Beta-blocking agents are commonly prescribed for cardiovascular conditions.

    Purpose of the Study:

    • To investigate the potential role of beta-blocking agents in provoking psoriasis.
    • To compare psoriasis activity in patients using beta-blockers versus a control group.

    Main Methods:

    • A cohort of 23 patients with psoriasis treated with beta-blocking agents was compared to a control group.
    • Psoriasis activity and age of onset were assessed.

    Main Results:

    • Seven out of 23 patients developed or experienced worsening of psoriasis after initiating beta-blocking therapy.
    • The mean age of psoriasis onset was significantly higher in the beta-blocker group (p < 0.001).

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  • Three out of four patients achieved remission after discontinuing beta-blocking medication.

    • Conclusions:

    • Beta-blocking agents may act as a provoking factor for psoriasis.
    • Discontinuation of beta-blockers can lead to remission of psoriasis symptoms.