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Cystic fibrosis in Jordan: a pilot study
Annals of Tropical Paediatrics
|December 1, 1984
Summary
Cystic fibrosis (CF) was diagnosed in 12 Jordanian children between 1976-1980, with a high mortality rate. Early diagnosis and care are crucial for managing this serious childhood illness.
Area of Science:
- Pediatrics
- Medical Genetics
- Public Health
Background:
- Cystic fibrosis (CF) is a serious genetic disorder.
- Recognition of CF in Jordan was limited during the study period.
Purpose of the Study:
- To determine the prevalence of cystic fibrosis in children admitted to Jordan University Hospital.
- To highlight the challenges in diagnosing and managing CF in Jordan.
Main Methods:
- Retrospective analysis of pediatric admissions from 1976-1980.
- Diagnosis based on clinical presentation, family history, and sweat chloride levels.
Main Results:
- 12 out of 15,314 children were diagnosed with CF.
- Five cases presented with meconium ileus.
- A high mortality rate of 41.7% was observed.
- Mean sweat chloride level was 97.6 mEq/l.
Conclusions:
- The prevalence of CF in Jordan may be underestimated.
- Early diagnosis and intensive care are essential for improving outcomes.
- Further prospective studies are needed to assess CF's impact on child health in Jordan.