[Characteristics of the secretory apparatus of memory T-cells]

It has been shown that by day 7--8 of cultivation, large lymphocytes and lymphoblasts disappear, the DNA synthesis and cytolytic activity decrease in lymphocyte suspension enriched with a fraction of lymphoblasts obtained on the 5th day of mixed lymphocyte culture. The cytoplasm of medium-size and small lymphocytes adsorbed on the surface of target-cells manifests no signs of secretion: there are no tubular structures or rough reticulum, the Golgi complex is underdeveloped. It is suggested that there is a relationship between the secretory apparatus and cytolytic activity of T-killers.