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Intranasal Administration of Recombinant Influenza Vaccines in Chimeric Mouse Models to Study Mucosal Immunity
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Persistence of cell-mediated immunity to influenza A virus in mice

R B Ashman

    Immunology
    |September 1, 1982
    PubMed

    Abstract:

    Cytotoxic T-cell (Tc) immunity to influenza A virus in mice persists for at least 2 years. Both T-helper (Th) and Tc cells are present and fully functional in old mice; however, the frequency of memory Tc-cell precursors declines with age.

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