[Bone sarcoma after radiotherapy. Apropos of 5 cases]

The authors describe 5 cases of bone sarcoma appearing between 9 and 29 years after radiation therapy. One patient was still surviving 21 years after above knee amputation, two died rapidly and two were lost to follow up. It is concluded that the incidence of post-radiation sarcoma is low but also that non-malignant tumours such as giant-cell tumours should never be treated by more than 1500 rads.