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Related Experiment Videos

Allergic contact dermatitis in two machinists.

M H Robertson, F J Storrs

    Archives of Dermatology
    |December 1, 1982
    PubMed
    Summary
    This summary is machine-generated.

    Allergic sensitivity to Tris Nitro, a biocide in metalworking fluids, caused chronic hand dermatitis in two machinists. Identifying this allergen is key to preventing future occupational skin disease.

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    Area of Science:

    • Occupational Dermatology
    • Chemical Toxicology

    Background:

    • Chronic hand dermatitis is common in machinists.
    • Most cases are attributed to irritant contact dermatitis.
    • Allergic contact dermatitis is less frequently identified but significant.

    Observation:

    • Two machinists presented with chronic hand dermatitis.
    • Patch testing revealed allergic sensitivity to Bronopol, a biocide found in cosmetics.
    • Patients identified Tris Nitro, a related biocide in their metalworking fluids, as the causative agent.

    Findings:

    • Allergic contact dermatitis to Tris Nitro (2-[hydroxymethyl]-2-nitro-1,3-propanediol) was confirmed in machinists.
    • Tris Nitro is used as a biocide in metalworking fluids to prevent microbial growth.
    • This highlights a specific occupational allergen in metalworking fluid formulations.

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    Implications:

    • Increased identification of allergens in metalworking fluids is anticipated with industry cooperation.
    • Prompt identification of causative agents like Tris Nitro is crucial for managing occupational dermatitis.
    • Collaboration with manufacturers can facilitate the use of safer, allergen-free cutting fluids.