Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

[Carnitine biosynthesis in mammals].

A Bach

    Reproduction, Nutrition, Developpement
    |January 1, 1982
    PubMed
    Summary
    This summary is machine-generated.

    Carnitine synthesis relies on precursors like lysine and methionine, requiring specific vitamins. Key organs like the liver and kidneys are crucial for this essential metabolic process.

    Related Concept Videos

    You might also read

    Related Articles

    Articles linked to this work by shared authors, journal, and citation graph.

    Sort by
    Same author

    Pre- and postweaning feeding strategies on growth and digestion of female Holstein calves.

    Journal of dairy science·2026
    Same author

    Amelioration of postpartum hyperketonemia using amino acids, cyanocobalamin, inositol, α-lipoic acid, or monensin during the transition period of dairy cows.

    Journal of dairy science·2026
    Same author

    Nutritional value of black soldier fly larvae oil in calf milk replacers.

    Journal of dairy science·2025
    Same author

    The oral microbiome as a proxy for feed intake in dairy cattle.

    Journal of dairy science·2024
    Same author

    Benefits of barley straw as a forage for dairy calves before and after weaning.

    Journal of dairy science·2023
    Same author

    Using compositional mixed-effects models to evaluate responses to amino acid supplementation in milk replacers for calves.

    Journal of dairy science·2021
    Same journal

    17 beta-estradiol secretion in normal and hypophysectomized chick embryos.

    Reproduction, nutrition, developpement·1989
    Same journal

    In vivo 13C NMR studies of glucose catabolism by isolated rumen bacteria.

    Reproduction, nutrition, developpement·1989
    Same journal

    Plasma lactose after weaning and its relationship with lactose content of milk, post-weaning plasma oestradiol-17 beta and weaning to mating interval in sows.

    Reproduction, nutrition, developpement·1989
    Same journal

    Effect of calcium and magnesium ions on the intestinal absorption of oleic acid in vitro.

    Reproduction, nutrition, developpement·1989
    Same journal

    [Marker transfer between food particles during digestive transit in the rabbit. Estimation method based on fecal granulometry].

    Reproduction, nutrition, developpement·1989
    Same journal

    Iodine nutrition in ewes: effects of low to high iodine intake on iodine content of biological fluids in pregnant and lactating ewes.

    Reproduction, nutrition, developpement·1989
    See all related articles

    Area of Science:

    • Biochemistry
    • Metabolic pathways
    • Nutritional science

    Background:

    • Long-chain fatty acid oxidation is dependent on carnitine, which facilitates mitochondrial entry.
    • Animals obtain carnitine through diet and endogenous synthesis to meet metabolic demands.

    Purpose of the Study:

    • To review current knowledge on endogenous carnitine synthesis.
    • To elucidate the precursors, biochemical pathway, and key organs involved in carnitine production.

    Main Methods:

    • Review of existing literature on carnitine biosynthesis.
    • Identification of precursor molecules and enzymatic steps.
    • Localization of synthesis pathways in animal and human tissues.

    Main Results:

    Related Experiment Videos

    • Carnitine synthesis originates from trimethyllysine, derived from lysine and methionine.
    • The pathway involves sequential methylation and hydroxylation steps, requiring vitamins like ascorbic acid, pyridoxine, and niacin.
    • Key tissues for intermediate steps include kidneys, while liver and testes are primary sites for the final hydroxylation step.

    Conclusions:

    • Carnitine synthesis is a complex, multi-step process influenced by precursor availability and enzyme activity.
    • Specific vitamins are essential cofactors for efficient carnitine production.
    • While synthesis pathways are identified, the relative contribution of different organs to overall carnitine levels requires further investigation.