Morphopathological findings in dog's acute toxoplasmosis

Toxoplasmosis was clinically diagnosed in two dogs of 4 and respectively 18 months. A seven-day treatment remained inefficient and the animals died. Autopsy revealed a global inflammation of the lung, with necrotic lesions of bronchial lymph nodes and acute hyperplastic reaction of the spleen. Histologically, there were identified a diffuse, serofibrinous inflammation of the lung with necrotic foci, fibrinoleucocytic and necrotic exudate of bronchial and portal lymph nodes, small necrotic or fibrinonecrotic foci of the liver and spleen, lymphoglial foci and edema at the base of the cerebellum. In myocardium, as well as in the above mentioned organs, toxoplamas are free or accumulated in cysts. Inoculation of infected lung material into mice and newborn dogs gave positive results.