[Coumarin-necroses: An allergic reaction or a local Sanarelli-Shwartzman-phenomenon? (author's transl)]

In a 70-year old woman presenting with extended coumarin-necroses on her right thigh and shin histological findings, immunofluorescence and coagulation-parameters favoured a mechanism closely related to a local Sanarelly-Shwartzman-reaction. A primary immunological process involving the vessel walls could be ruled out.