[Frequency, relevance and latency of chemical allergy in hospitalized patients in Budapest]

Epicutaneous tests were performed 1979 using a standard test series of 31 substances on 436 hospitalized patients. The positive results were analysed for relevance and latency. Occupational and environmental origin of sensitization was looked for in both sexes. The order of allergens causing contact dermatitis in women was: Dichromate, phenylbutazone, cobalt (as concomitant allergy?), balsam of Peru, p-phenylene diamine, chloramphenicol, phenyl-isopropyl-p-phenylene diamine, N-phenyl-cyclohexyl-p-phenylene diamine (as concomitant allergy?), mercury amidochlorate, formaldehyde, mercury bichloride (as concomitant allergy?). In men the order of frequency was: dichromate, phenyl-isopropyl-p-phenylene diamine, N-phenyl-cyclohexyl-p-phenylene diamine (as concomitant allergy?), cobalt (as concomitant allergy?), p-phenylene diamine, chloramphenicol, formaldehyde, phenylbutazone, balsam of Peru, mercury amidochlorate, mercury bichloride (as concomitant allergy?). The mode and degree of exposure are important factors influencing the composition of the spectrum of allergens. It is essential to distinguish between relevant and latent sensitization primarily in occupational exposure when decisions concerning the patient's future occupation must be made.