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Continuous Manual Exchange Transfusion for Patients with Sickle Cell Disease: An Efficient Method to Avoid Iron Overload
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Continuous Manual Exchange Transfusion for Patients with Sickle Cell Disease: An Efficient Method to Avoid Iron Overload

Published on: March 14, 2017

[Treatment of iron deficiency anemia with ferrosulfate serin komplex (author's transl)]

G Weippl

    Padiatrie Und Padologie
    |January 1, 1978
    PubMed

    Insights

    Ferrosulfate serin complex effectively treats iron deficiency anemia in children. This iron supplement offers improved absorption, requiring a low dose with minimal side effects.

    Area of Science:

    • Pediatric Hematology
    • Nutritional Anemia
    • Pharmacological Treatments

    Context:

    • Iron deficiency anemia (IDA) is a prevalent condition in children, impacting growth and development.
    • Effective treatment strategies are crucial for managing IDA and its associated complications.
    • Ferrosulfate serin complex presents a novel therapeutic option for pediatric IDA.

    Purpose:

    • To evaluate the efficacy and safety of ferrosulfate serin complex in treating iron deficiency anemia in pediatric patients.
    • To assess the hemoglobin increase rates in different subgroups of anemic children.
    • To determine the optimal dosage and tolerability of the ferrosulfate serin complex.

    Summary:

    • A study involving 217 children (8 months to 12 years) with IDA treated with ferrosulfate serin complex demonstrated significant hemoglobin increases.
    • Children with simple IDA showed a daily hemoglobin rise of 0.082 g/100 ml, while those with severe anemia or hypoxic polycythemia experienced daily increases of 0.21 mg/100 ml and 0.16 g/100 ml, respectively.
    • The complex's enhanced absorption allowed for a low dosage of 3 mg/kg/d, resulting in a low incidence of side effects.

    Impact:

    • Ferrosulfate serin complex provides an effective and well-tolerated treatment for pediatric iron deficiency anemia.
    • The improved absorption and low dosage may enhance patient compliance and reduce treatment-related adverse events.
    • This study highlights a promising therapeutic approach for improving hematological parameters in anemic children.

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