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Iopamidol in lumbar myelography
Surgical Neurology
|August 1, 1983
Summary
Iopamidol, a new contrast agent, demonstrated safety and efficacy in lumbar myelography. Most side effects were mild and transient, indicating its potential as a safe option for this diagnostic procedure.
Area of Science:
- Radiology
- Neuroradiology
- Medical Imaging
Background:
- Iopamidol is a novel nonionic, water-soluble contrast agent.
- It is undergoing clinical trials for intravascular and intrathecal applications.
Purpose of the Study:
- To evaluate the safety and efficacy of iopamidol in lumbar myelography.
- To assess adverse reactions associated with iopamidol use.
Main Methods:
- 12 patients underwent lumbar myelography using iopamidol (200 mg I/mL).
- Up to 12 mL of the contrast agent was administered per patient.
Main Results:
- Myelograms were highly satisfactory.
- No serious adverse reactions were observed.
- The most common side effect was mild, transient headache (7/12 patients). Other mild, self-limited reactions included nausea, back pain, and blood pressure fluctuations.
Conclusions:
- Iopamidol is a safe and convenient agent for lumbar myelography.
- Its favorable safety profile supports its use in clinical practice.