Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Search research articles

Related Experiment Videos

[Lipoprotein (a)].

F Thuillier, F Rousselet

Annales De Biologie Clinique

|January 1, 1983

Summary

This summary is machine-generated.

Lipoprotein(a) [Lp(a)] is a unique lipoprotein linked to increased coronary heart disease risk. High Lp(a) levels, above 300 mg/l, may indicate a significant risk in individuals with normal lipid levels.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Dihydropyrimidine dehydrogenase phenotype-guided dose individualization of fluoropyrimidine in gastrointestinal cancers: PRODIGE100-UCGI48-FUDOSE phase II study.

Digestive and liver disease : official journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver·2026

Same author

[Calcified bullet thrombus of the inferior vena cava and left renal vein in an adult].

Journal des maladies vasculaires·2016

Same author

[Seventeenth-century brick ovens in Tourcoing, Nord].

Revue du Nord·2012

Same author

[Endocarditis due to Coxiella burnetti despite the absence of obvious exposure].

La Revue de medecine interne·2011

Same author

Selenoprotein P, rather than glutathione peroxidase, as a potential marker of septic shock and related syndromes.

European surgical research. Europaische chirurgische Forschung. Recherches chirurgicales europeennes·2009

Same author

[PSA kinetics after radiotherapy].

Annales de biologie clinique·2009

Same journal

[The role of the heart-on-a-chip to drug evaluation].

Annales de biologie clinique·2026

Same journal

A morphology-driven proof-of-concept study linking interphase nuclear abnormalities to dicentric-mediated genomic instability.

Annales de biologie clinique·2026

Same journal

Analytical validation and clinical concordance of Diazyme free light chain assays on the Cobas® platform compared with Freelite™.

Annales de biologie clinique·2026

Same journal

Small-cell secondary plasma cell leukemia mimicking low-grade B-cell lymphoma.

Annales de biologie clinique·2026

Same journal

[Multiple myeloma and analytical discrepancy in serum free light chain assay: a case report].

Annales de biologie clinique·2026

Same journal

[Summary of the 34th National Conference of the National College of Hospital Biochemistry].

Annales de biologie clinique·2026

See all related articles

Area of Science:

Biochemistry
Genetics
Cardiology

Context:

Lipoprotein(a) [Lp(a)] is a distinct lipoprotein with very high density.
Its structure includes apo B, specific apoproteins, and a sialic acid-rich carbohydrate chain.
Lp(a) is inherited through autosomal dominant or polygenic mechanisms.

Purpose:

To characterize the unique properties of Lp(a).
To investigate the genetic transmission of Lp(a).
To explore the diagnostic and clinical significance of Lp(a) levels.

Summary:

Lp(a) possesses unique apoproteins and a sialic acid-rich carbohydrate chain, differing from LDL and HDL.
Its synthesis is constant, and it is not metabolized into other lipoproteins.
Radioimmunoassay is the preferred method for Lp(a) quantification, especially at low levels.

Related Experiment Videos

Impact:

Elevated Lp(a) levels (≥300 mg/l) are associated with increased coronary heart disease risk.
In vitro studies suggest Lp(a) selectively binds to glycosaminoglycans (GAG) in the presence of calcium ions.
Understanding Lp(a) may lead to improved cardiovascular risk assessment and management strategies.