[Radionuclide complex in vitro studies in the diagnosis of lung cancer]

The results of studies on ventilation and capillary blood flow are analyzed in 89 lung carcinoma patients and 28 patients with nonmalignant lung diseases by using 133Xe and 99mTc-MAA. The studies were conducted with the help of scintillation radiometers: multidetector unit and a gamma-chamber. The concentration in the blood serum of biologically active agents: CEA, PTH, immunoglobulin E, ferritin, hydrocortisone and beta2-microglobulin was determined in 76 cancer patients and 19 patients with nontumorous lung diseases. It has been established that visualization with 99mTc-MMA and studies with 133Xe are of utmost informative value. There was not a single specific marker for lung carcinoma that could be independently used for the diagnosis of this pathology. It is appropriate that they should be used in combination with other radionuclide methods and instrumental examination. Besides, they can be recommended for control over therapeutic efficacy.