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Normal hematologic values obtained with a Coulter counter, model S
Insights
Hematologic values from 6,887 outpatients were analyzed. Newer methods yielded slightly lower hemoglobin, hematocrit, and red blood cell counts compared to established norms.
Area of Science:
- Clinical pathology
- Hematology
Background:
- Hematologic parameters are crucial for diagnosing and monitoring various health conditions.
- Establishing accurate reference ranges is essential for reliable clinical interpretation.
Purpose of the Study:
- To survey hematologic values in a large outpatient population using the Coulter Counter, Model S.
- To compare these values against commonly accepted normal ranges.
Main Methods:
- Analysis of blood specimens from 6,887 outpatients (men, women, and children).
- Exclusion of patients seeing nephrologists, hematologists, and oncologists.
- Utilized the Coulter Counter, Model S for automated hematologic analysis.
Main Results:
- Mean values for white blood cell count, mean corpuscular volume, mean corpuscular hemoglobin, and mean corpuscular hemoglobin concentration aligned well with established normal values.
- Mean values for hemoglobin, hematocrit, and red blood cell count were observed to be slightly lower than commonly accepted normal means.
Conclusions:
- The Coulter Counter, Model S provides reliable hematologic values.
- Slightly lower mean values for hemoglobin, hematocrit, and RBC count may reflect advancements in analytical accuracy.
- Further investigation into updated reference ranges may be warranted.
Abstract:
A survey was made of hematologic values obtained with the Coulter Counter, Model S, at American Medical Laboratories, Inc. Blood specimens from 6,887 outpatient men, women, and children were analyzed according to age and sex. Patients being seen by nephrologists, hematologists, and oncologists were excluded from the study. The mean values for white blood cell counts, mean corpuscular volume, mean corpuscular hemoglobin, and mean corpuscular hemoglobin concentration correlated well with values frequently quoted as normal. However, the mean values for hemoglobin, hematocrit, and red blood cell counts were slightly lower than the commonly accepted normal mean values. This may be a result of newer and more accurate methods of hematologic analysis.