Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Lymph drainage from the vulva.

T Iversen, M Aas

    Gynecologic Oncology
    |October 1, 1983
    PubMed
    Summary
    This summary is machine-generated.

    Preoperative lymphatic mapping in cervical cancer patients reveals most radiotracer drains to ipsilateral pelvic lymph nodes. Some contralateral spread occurs, particularly from the anterior labia, highlighting potential bilateral lymphatic pathways.

    Related Concept Videos

    You might also read

    Related Articles

    Articles linked to this work by shared authors, journal, and citation graph.

    Sort by
    Same author

    Whole blood long-chain n-3 fatty acids as a measure of fish oil compliance in children with acute lymphoblastic leukemia: a pilot study.

    Prostaglandins, leukotrienes, and essential fatty acids·2022
    Same author

    PDRMIP: A Precipitation Driver and Response Model Intercomparison Project, Protocol and preliminary results.

    Bulletin of the American Meteorological Society·2020
    Same author

    A PDRMIP multi-model study on the impacts of regional aerosol forcings on global and regional precipitation.

    Journal of climate·2020
    Same author

    Tobacco smoking and other substance use disorders associated with recurrent suicide attempts in bipolar disorder.

    Journal of affective disorders·2019
    Same author

    An association between YKL-40 and type 2 diabetes in psychotic disorders.

    Acta psychiatrica Scandinavica·2018
    Same author

    Scattering media characterization with phase-only wavefront modulation.

    Optics express·2018
    Same journal

    Toward precision prognosis: Predicting recurrence-free survival in high-grade serous ovarian cancer patients using multi-time point clinical and computed tomography radiomics data.

    Gynecologic oncology·2026
    Same journal

    Adjunctive sodium-glucose cotransporter 2 (SGLT2) inhibitors with progestins and endometrial cancer risk in benign uterine diseases and hyperplasia.

    Gynecologic oncology·2026
    Same journal

    Updated patient-reported outcomes and the effect of disease progression on health-related quality of life in the PRIMA/ENGOT-OV26/GOG-3012 trial of niraparib first-line maintenance therapy in patients with newly diagnosed advanced ovarian cancer.

    Gynecologic oncology·2026
    Same journal

    PRO-PLATINUM: A randomized, double-blind, placebo controlled study to investigate the efficacy of a probiotic intervention on the gut and vaginal microbiome of ovarian cancer patients undergoing treatment with platinum chemotherapy.

    Gynecologic oncology·2026
    Same journal

    A second chance for the second look: Feasibility of laparoscopic HIPEC at the conclusion of upfront treatment for epithelial ovarian cancer.

    Gynecologic oncology·2026
    Same journal

    Prognostic impact of time to first recurrence in low-grade serous ovarian carcinoma: A multicentric retrospective study from the French TMRG network.

    Gynecologic oncology·2026
    See all related articles

    Area of Science:

    • Oncology
    • Nuclear Medicine
    • Surgical Anatomy

    Background:

    • Accurate lymphatic staging is crucial for cervical cancer treatment.
    • Understanding vulvar lymphatic drainage patterns informs surgical and radiation strategies.
    • Previous studies show variable lymphatic pathways in gynecologic malignancies.

    Purpose of the Study:

    • To delineate the lymphatic drainage pathways from the vulva to pelvic lymph nodes in cervical cancer patients.
    • To assess the incidence and extent of bilateral lymphatic spread.
    • To identify specific vulvar injection sites associated with contralateral lymphatic drainage.

    Main Methods:

    • Preoperative injection of 99mTc-colloid into vulvar areas of 54 cervical cancer patients (Stage Ib).
    • Control injections into the axilla for three patients.

    Related Experiment Videos

  • Radioactivity measurement in groins and pelvis using a scintillation camera and in removed pelvic lymph nodes using a well counter.

    • Main Results:

    • Vast majority of radioactivity localized to ipsilateral pelvic lymph nodes.
    • Significant contralateral lymphatic drainage observed in 67% of patients, especially from anterior labia.
    • Medial external iliac lymph nodes showed highest uptake (73%); direct clitoral pathway to pelvic nodes not identified.

    Conclusions:

    • Vulvar lymphatic drainage in cervical cancer is predominantly ipsilateral but frequently involves contralateral pelvic nodes.
    • Anterior labial injections are associated with higher rates of bilateral drainage.
    • Findings suggest probable anastomoses between presacral and/or common iliac nodes, impacting staging accuracy.