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Postoperative deep vein thrombosis--early diagnosis and prophylaxis
Japanese Circulation Journal
|January 1, 1984
Summary
Deep vein thrombosis (DVT) incidence is lower in Japan. Key risk factors include age over 50, malignancy, and pre-existing hypercoagulability, with compression devices proving most effective for prevention.
Area of Science:
- Vascular Surgery
- Thrombosis Research
- Clinical Medicine
Background:
- Postoperative deep vein thrombosis (DVT) remains a significant clinical concern.
- Variations in DVT incidence across different geographic regions suggest underlying contributing factors.
Purpose of the Study:
- To investigate the incidence and risk factors of postoperative DVT in Japanese surgical and gynecological patients.
- To evaluate the efficacy of preventive measures for DVT.
Main Methods:
- Utilized the 125I-fibrinogen method and beta-thromboglobulin measurements.
- Assessed patients undergoing surgical and gynecological procedures.
- Compared DVT incidence with Western countries and analyzed risk factors.
Main Results:
- DVT incidence was notably lower in Japan compared to Western countries.
- Significant risk factors identified: age (≥50 years) and malignant diseases.
- Preoperative hypercoagulability and impaired postoperative fibrinolysis were critical factors.
- Graded compression stockings reduced DVT incidence from 13.5% to 4.0%.
Conclusions:
- Japanese patients exhibit a lower incidence of postoperative DVT.
- Age, malignancy, and hemostatic alterations are key risk factors.
- Intermittent pneumatic compression devices are the most effective preventive strategy for high-risk patients.