Related Experiment Videos
Morbilliform skin eruption owing to diethylstilbestrol
The Journal of Urology
|April 1, 1984
Summary
A patient with advanced prostate cancer developed a morbilliform skin rash from diethylstilbestrol treatment. The rash resolved upon discontinuing the medication, highlighting a rare drug-induced dermatosis.
Area of Science:
- Oncology
- Dermatology
- Pharmacology
Background:
- Diethylstilbestrol (DES) is a synthetic estrogen used in treating advanced prostate cancer.
- Adverse drug reactions, including dermatological manifestations, can occur with DES therapy.
Observation:
- A case of morbilliform skin eruption and urticaria is presented in a male patient with stage D prostate cancer.
- The eruption appeared upon repeated administration of diethylstilbestrol and subsided after its withdrawal.
Findings:
- Diethylstilbestrol can induce a morbilliform drug eruption in male patients.
- This case highlights an unusual cutaneous side effect of diethylstilbestrol in prostate cancer management.
Implications:
- Awareness of this potential side effect is crucial for clinicians managing prostate cancer patients on diethylstilbestrol.
- Further investigation into the mechanisms of DES-induced dermatosis may be warranted.