Related Experiment Videos
Shunt nephritis: a report on five children
Child'S Brain
|January 1, 1984
Insights
Antibiotic therapy and shunt removal improved kidney function in most children with glomerulonephritis and infected shunts. Some cases required advanced renal replacement therapy.
Area of Science:
- Pediatric Nephrology
- Infectious Diseases
- Nephrology
Background:
- Glomerulonephritis can lead to renal insufficiency in children.
- Ventriculoatrial shunts are used for hydrocephalus but can become infected.
- Infected shunts pose a risk for systemic complications, including renal involvement.
Observation:
- Five pediatric cases of glomerulonephritis associated with infected ventriculoatrial shunts were analyzed.
- Three patients showed improved renal function following antibiotic treatment and shunt removal.
- One patient with severe glomerulonephritis experienced rapidly progressive renal insufficiency.
Findings:
- Successful management of renal failure was achieved through hemodialysis and kidney transplantation in a severe case.
- Antibiotic therapy and surgical intervention (shunt removal) are crucial for managing infected shunts in children with glomerulonephritis.
- Mortality in one case was attributed to extrarenal complications during a septic episode.
Implications:
- Early diagnosis and intervention are vital for children with glomerulonephritis and infected shunts.
- Aggressive management, including renal replacement therapy, may be necessary for severe cases.
- Understanding the interplay between shunt infections and renal disease is critical for pediatric care.
Abstract:
Of 5 children with glomerulonephritis with infected ventriculoatrial shunt, 3 had improved renal function after antibiotic therapy and removal of the infected shunt. 1 patient with endoextracapillary proliferative glomerulonephritis with 70% glomerular crescents developed a rapidly progressive renal insufficiency. Renal failure was successfully managed by hemodialysis and kidney transplantation. 1 patient died from extrarenal causes in the course of a septic episode.