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[Lympho-epithelial interactions in the thymus during development of radio-induced lymphomas in C57BL mice]

M P Houben-Defresne, P Lenaerts, R Greimers

    Comptes Rendus Des Seances De La Societe De Biologie Et De Ses Filiales
    |January 1, 1984
    PubMed

    In C57BL/Ka mice, leukemogenic fractionated whole-body X-irradiation induces alterations of the lymphoepithelial interactions normally found in the Thymic Nurse Cells (TNCs) and leads to the disappearance of these complexes. This phenomenon is due to the disturbances of thymic lymphopoiesis caused by modifications of bone marrow prothymocytes and of the epithelial component of TNCs.

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