Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Enzyme polymorphism in placentae from northern Greece.

A Kouvatsi, C Triantaphyllidis

    Human Heredity
    |January 1, 1984
    PubMed
    Summary

    Genetic variations in placental samples from Northern Greece were analyzed. While GOTm and GOTs gene frequencies align with other Caucasian groups, EsD and PGMa11 allele frequencies are notably lower in this region compared to broader European populations.

    Related Concept Videos

    You might also read

    Related Articles

    Articles linked to this work by shared authors, journal, and citation graph.

    Sort by
    Same author

    Clinical response to non-surgical periodontal treatment in patients with interleukin-6 and interleukin-10 polymorphisms.

    Medicina oral, patologia oral y cirugia bucal·2017
    Same author

    Antigen receptor stereotypy across B-cell lymphoproliferations: the case of IGHV4-59/IGKV3-20 receptors with rheumatoid factor activity.

    Leukemia·2011
    Same author

    Microsatellite variability of wild and farmed populations of Sparus aurata.

    Journal of fish biology·2010
    Same author

    Intraclonal diversification of immunoglobulin light chains in a subset of chronic lymphocytic leukemia alludes to antigen-driven clonal evolution.

    Leukemia·2010
    Same author

    The ACE I/D polymorphism in elite Greek track and field athletes.

    The Journal of sports medicine and physical fitness·2010
    Same author

    Molecular evidence for EBV and CMV persistence in a subset of patients with chronic lymphocytic leukemia expressing stereotyped IGHV4-34 B-cell receptors.

    Leukemia·2009

    Area of Science:

    • Human genetics
    • Population genetics
    • Biochemical genetics

    Background:

    • Genetic diversity is crucial for understanding population history and health.
    • Placental genetics offers insights into maternal-fetal interactions and population-specific adaptations.
    • Previous studies have established baseline genetic frequencies for various loci in different Caucasian populations.

    Purpose of the Study:

    • To investigate the genetic variations at specific loci (PGM1, GOTm, GOTs, EsD) in a Northern Greek population.
    • To compare these gene and allele frequencies with those reported in other Caucasian and European populations.
    • To identify any unique genetic patterns or deviations within the studied Northern Greek cohort.

    Main Methods:

    • Analysis of genetic polymorphisms using placental samples.
    • Typing of enzymes encoded by PGM1, GOTm, GOTs, and EsD genes.
    • Calculation and comparison of gene and allele frequencies.

    Main Results:

    • Gene frequencies for GOTm (Glutamate oxaloacetate transaminase, mitochondrial) and GOTs (Glutamate oxaloacetate transaminase, soluble) in Northern Greece are comparable to other Caucasian populations.
    • Allele frequencies for EsD (Esterase D) and PGMa11 (Phosphoglucomutase 1, allele 11) were found to be lower in the Northern Greece samples than in other European populations.
    • This suggests potential regional variations in the distribution of these specific genetic markers.

    Conclusions:

    • The genetic landscape of Northern Greece shows similarities with other Caucasian populations for certain enzyme loci (GOTm, GOTs).
    • However, a lower frequency of EsD and PGMa11 alleles indicates a distinct genetic profile for these markers in the Northern Greek population compared to other European groups.
    • Further research is warranted to explore the implications of these observed genetic differences.

    Related Experiment Videos