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Regional mapping of liver type 6 phosphofructokinase isoenzyme on chromosome 21
Human Genetics
|January 1, 1984
Abstract:
Among several cases of partial monosomies and full and partial trisomies 21, the enzymatic activity of phosphofructokinase (PFK) is increased only in 21q21----21pter trisomy with a (T21/N) ratio equal to 1.35 and decreased in monosomy 21q21----21pter. These results suggest that the human gene for liver-type PFK is located between 21q21 and 21pter.
