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Updated: Sep 21, 2026

Analysis of Pulmonary Dendritic Cell Maturation and Migration during Allergic Airway Inflammation
Published on: July 23, 2012
Suppressor function in respiratory allergic diseases. Deficient concanavalin A-induced suppressor cell activity in
Abstract:
Concanavalin A (Con A)-induced suppressor action against the proliferative response of autologous lymphocytes to phytohemagglutinin (PHA) was examined in the peripheral blood lymphocytes of 32 patients with bronchial asthma, 10 patients with allergic rhinitis and then compared with 12 simultaneously studied healthy normals. Twenty-two of 32 patients (68.8%) with bronchial asthma, 8 of 10 patients (80%) with allergic rhinitis demonstrated deficient Con-A-induced suppressor function. Abnormal suppressor cell functions could play an important role in the pathogenesis of respiratory allergic states.
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