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Updated: Aug 13, 2026

Whole-mount Immunohistochemical Analysis for Embryonic Limb Skin Vasculature: a Model System to Study Vascular Branching Morphogenesis in Embryo
Published on: May 20, 2011
[Bone and skin vascularization of the lower 4th of the leg]
Abstract:
The authors have studied the vascular network of bone and skin in the lower third of the leg by injection of methyl methacrylate in 31 cadavers. The vascular supply of the bone is given by metaphyseal and epiphyseal arteries branching from the main trunks. Different types of vascular network are described. The vascular supply of the skin is given by a subaponeurotic plexus with branches crossing in areas which can be considered as radiating vascular hili. These hili should be preserved during surgical operations. Conclusions are given concerning the security of the surgical approaches at the lower third of the leg.
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