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[Cancer of the thyroid in children. 14 cases]
Presse Medicale (Paris, France : 1983)
|March 10, 1984
Summary
Pediatric thyroid cancer, often presenting as a cold nodule, has a good prognosis in children. Treatment involves conservative surgery, radioactive iodine for metastases, and hormone therapy, avoiding radiation therapy.
Area of Science:
- Pediatric Endocrinology
- Oncology
- Nuclear Medicine
Background:
- Thyroid gland carcinoma in children is rare but requires specific management strategies.
- Early diagnosis and appropriate treatment are crucial for favorable outcomes.
Purpose of the Study:
- To review cases of pediatric thyroid carcinoma.
- To analyze diagnostic findings and treatment outcomes.
- To provide recommendations for optimal management.
Main Methods:
- Retrospective review of fourteen pediatric thyroid carcinoma cases.
- Analysis of scintigraphy findings (cold nodule, diffuse uptake).
- Evaluation of clinical presentation, treatment modalities, and prognosis.
Main Results:
- Mean age of patients was 10 years.
- Scintigraphy revealed a cold nodule in 10 cases and diffuse uptake in 3, indicating undifferentiated carcinoma.
- Clinical risks include thyroid gland alterations and lymph node involvement.
- Favorable long-term prognosis observed in pediatric patients.
- Pulmonary metastases responded well to radioactive iodine therapy.
- Continuous hormone treatment effectively suppressed TSH secretion.
Conclusions:
- Conservative surgical treatment is justified due to the favorable long-term prognosis in children.
- Radioactive iodine is effective for pulmonary metastases.
- Complete TSH suppression via hormonal treatment is essential.
- Anticancerous irradiation carries potential dangers and should be used cautiously.