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[Viral and Mycoplasma-induced glomerulopathies in children]
Abstract:
Morphological examinations of kidneys from 227 children who had suffered from various generalized acute viral respiratory infections and mycoplasmosis established in 79 cases pathology of renalglomeruli, namely viral and mycoplasmic glomerulopathies. In 52 cases they corresponded to various forms of glomerulonephritis. The detection of deposites of immunoglobulins, virus and mycoplasma antigens suggest the association of these changes with the above-mentioned infections. Besides, 27 children showed peculiar lesions of the renal glomeruli, associated with the cytopathic effect of respiratory viruses and mycoplasma.
Insights
Viral and mycoplasma infections can cause kidney damage in children. Studies show these infections lead to glomerulopathies and glomerulonephritis, impacting renal health.
Area of Science:
- Nephrology
- Pediatric Nephrology
- Infectious Diseases
Context:
- Generalized acute viral respiratory infections and Mycoplasma pneumoniae are common in children.
- Kidney involvement is a potential complication of these infections.
- Morphological examination provides insight into renal pathology.
Purpose:
- To investigate the morphological changes in the kidneys of children with viral respiratory infections and mycoplasmosis.
- To identify the prevalence and nature of renal glomerulopathies associated with these infections.
- To explore the pathogenetic links between infections and observed kidney lesions.
Summary:
- Morphological examination of 227 children revealed renal glomerulopathies in 79 cases, linked to viral and mycoplasmic infections.
- 52 cases presented as various forms of glomerulonephritis.
- Immunoglobulin, virus, and mycoplasma antigen deposits suggest infection-associated changes, with 27 children showing cytopathic lesions.
Impact:
- Highlights the potential for significant kidney pathology following common childhood infections.
- Underscores the importance of considering renal complications in pediatric respiratory infections.
- Provides morphological evidence linking viral/mycoplasmal infections to glomerulopathies and glomerulonephritis.