Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Lithium as an immunologic adjuvant.

L Shenkman, W Borkowsky, B Shopsin

    Medical Hypotheses
    |January 1, 1980
    PubMed
    Summary
    This summary is machine-generated.

    Lithium stimulates key immune cell functions like lymphocyte proliferation and macrophage phagocytosis in lab studies. This immune enhancement occurs at therapeutic lithium doses, suggesting potential as an immune booster.

    Related Experiment Videos

    Related Concept Videos

    You might also read

    Related Articles

    Articles linked to this work by shared authors, journal, and citation graph.

    Sort by
    Same author

    Non-invasive method for assessment of inflammation.

    Biomedical optics express·2023
    Same author

    Impact of Fitness Status on the Optically Measured Hemodynamic Indexes.

    Journal of healthcare engineering·2018
    Same author

    The EPIICAL project: an emerging global collaboration to investigate immunotherapeutic strategies in HIV-infected children.

    Journal of virus eradication·2016
    Same author

    Transmission of methicillin-resistant Staphylococcus aureus via deceased donor liver transplantation confirmed by whole genome sequencing.

    American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons·2014
    Same author

    [SKF index as a new non-invasive parameter for the evaluation of the biological age for healthy and sick people].

    Advances in gerontology = Uspekhi gerontologii·2013
    Same author

    Metabolic abnormalities and viral replication are associated with biomarkers of vascular dysfunction in HIV-infected children.

    HIV medicine·2011
    Same journal

    Calcitonin Gene-Related Peptide-Induced Central Sensitization: A Hypothesis for Long COVID Symptoms.

    Medical hypotheses·2026
    Same journal

    Subclinical mastitis during lactation: a modifiable risk factor for breast cancer?

    Medical hypotheses·2025
    Same journal

    The Role of Hemispheric Sensory Shifts: Impacts on Stretch Reflex and Motor Plasticity Post-Stroke.

    Medical hypotheses·2025
    Same journal

    Neuron-Targeted Exosome Therapy: A Novel Approach for Treating Cardiogenic Dementia via RyR2 Inhibition.

    Medical hypotheses·2025
    Same journal

    How the Somatosensory System Adapts to the Motor Change in Stroke: A Hemispheric Shift?

    Medical hypotheses·2024
    Same journal

    Unstable Plaque is a Treatable Cause of Cognitive Decline.

    Medical hypotheses·2024
    See all related articles

    Area of Science:

    • Immunology
    • Pharmacology

    Background:

    • Lithium is known to inhibit adenylate cyclase.
    • Adenylate cyclase plays a role in regulating cellular immune responses.

    Observation:

    • Lithium stimulates in vitro immune responses.
    • Observed effects include lymphocyte proliferation, T-cell rosette formation, and macrophage phagocytosis.

    Findings:

    • Lithium enhances multiple indices of immune function at therapeutic concentrations.
    • These effects were observed in vitro, mimicking clinical lithium levels.

    Implications:

    • Lithium may serve as an immune adjuvant.
    • Potential therapeutic applications exist for immune deficiency disorders, especially those linked to elevated cyclic AMP (c-AMP).