Angiotensin-converting enzyme in uveitis and sarcoidosis

Serum angiotensin-converting enzyme (SACE) was studied in a group of 29 sarcoidosis patients (among whom five had uveitis) and in 22 patients with non-sarcoid uveitis. SACE was normal in all non-sarcoid patients and elevated in 62 per cent of the patients with sarcoidosis. Thus an elevated SACE is closely linked to sarcoidosis and may be a valuable tool in evaluating patients with uveitis in search of a sarcoid origin.