[Tiapride and painful attacks of drepanocytosis (author's transl)]

Patients with drepanocytosis require frequent hospitalization for treatment of the severe attacks of pain induced by the disease process. Therapy is often of limited extent and vasodilators, the usual medication employed, do not give very satisfactory results. A study with tiapride demonstrated that this compound could be effective both for curative and preventive treatment, probably in relation to its direct action on pain centres. Very good results were obtained in 11 cases, good results in 8, moderate results in 2, and no result in one case only.