Related Experiment Video
Updated: Sep 2, 2026
08:39
Operant Sensation Seeking in the Mouse
Published on: November 10, 2010
The albino locus produces abnormal responses to opiates in the mouse
European Journal of Pharmacology
|November 21, 1980
Abstract:
Pedigreed inbred lines of pigmented mice were compared with albino lines differing at either a single locus or by a chromosomal segment of interest, for their responses to morphine. In either of two tests, behavioral activation or reduction in core temperature, albino mice were aberrant in their responses, demonstrating reliably less sensitivity to morphine than closely related pigmented lines. These findings suggest the need for caution in the use of albino lines in opiate research.
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