Expression of type-common envelope antigens by herpes simplex virus type 2-transformed hamster cells

At least ten polypeptides were detected on the surface of the herpes simplex virus type 1 (HSV-1) virion. Two of these polypeptides, having molecular weights of 30,000 and 33,000, were identified in two herpes simplex virus type 2-transformed cell lines (333-8-9 and 333-2-29) by immunoprecipitation and SDS-PAGE. The same two virion polypeptides previously were shown to be present in an HSV-1-transformed cell line (14-012-8-1, T-10). These observations suggest that genetic information coding for these polypeptides is in close proximity to that portion of the virus genome involved in transformation.