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Effect of sodium diethyl dithiocarbamate on mitogen induced lymphoproliferation "in vitro"
Biomedicine / [Publiee Pour L'A.A.I.C.I.G.]
|December 1, 1980
Abstract:
Sodium diethyl dithiocarbamate (DTC) is a low molecular weight sulphur compound which has been shown to be an adjuvant of immunity in vivo. In this report, DTC was shown to inhibit in vitro DNA-synthesis of human peripheral blood lymphocytes stimulated by phytohemagglutinin or concanavalin A. DTC could act directly at the cellular level and indirectly by interfering with culture medium or lectins.