Total body irradiation in oat cell carcinoma of the bronchus

Total body irradiation (TBI) as a systemic therapy has been used in controlling subclinical metastases in oat cell carcinoma of the bronchus (limited disease). Preliminary results suggest that a delay occurs in the development of brain metastases as not a single patient developed this in this series. As eventually almost all patients developed distant metastases, further maintenance chemotherapy is recommended.