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[Possible interaction between the synaptic and pacemaker mechanisms of electrical activity in the bursting neuron of
Abstract:
Membrane hyperpolarization in neuron RPal of Helix pomatia was induced by short-duration pulses of inward current, spontaneous IPSP arising in the neuron, stimulation of the anal nerve evoking IPSP in the neuron. Short-duration hyperpolarization of the membrane was demonstrated to trigger a regenerative hyperpolarization lasting up to several seconds. The time course of IPSP arising in the neuron spontaneously or after stimulation of the anal nerve was similar to that of the regenerative hyperpolarization triggered by the inward current pulse. Suggestion is put forward that regenerative hyperpolarization linked with involvement of endogenous mechanisms can be triggered not only by short duration hyperpolarization of the neuronal membrane but also by hyperpolarization occurring during IPSP generation.