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Beta-adrenergic receptors of human polymorphonuclear leukocytes
Research Communications in Chemical Pathology and Pharmacology
|March 1, 1981
Abstract:
125I-iodohydroxybenzylpindolol (IHYP) is a beta-adrenergic antagonist used as a ligand for the characterization of beta-adrenergic receptors in various cell preparations. Since IHYP may be adsorbed to surfaces such as test tubes and pipet tips, it is necessary to measure the actual free concentration of IHYP in the incubation solution. With this modification, the number of beta-adrenergic receptors in human peripheral PMNs can be determined with greater precision.