Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Do patients take digoxin?

G D Johnston, J G Kelly, D G McDevitt

    British Heart Journal
    |January 1, 1978
    PubMed
    Summary
    This summary is machine-generated.

    Many patients struggle with proper digoxin dosing, with half taking it incorrectly. This highlights significant issues in communication between doctors and patients regarding medication adherence.

    Related Concept Videos

    You might also read

    Related Articles

    Articles linked to this work by shared authors, journal, and citation graph.

    Sort by
    Same author

    Biliary excretion and enterohepatic recirculation of practolol in man.

    Irish journal of medical science·2016
    Same author

    Erroneous plasma "cortisol" values in Addison's disease : A problem of the fluorimetric assay of 11-OH corticosteroids.

    Irish journal of medical science·2016
    Same author

    The concept of primary prevention: Creating new paradigms.

    The journal of primary prevention·2013
    Same author

    The assessment of β-adrenoceptor blocking drugs in hyperthyroidism.

    British journal of clinical pharmacology·2012
    Same author

    Intrinsic heart rate on exercise and the measurement of beta-adrenoceptor blockade.

    British journal of clinical pharmacology·2012
    Same author

    New developments in antihypertensive drugs.

    Trends in cardiovascular medicine·2011
    Same journal

    Cardiac enlargement with bradycardia in recruits.

    British heart journal·2010
    Same journal

    Paravertebral block and the electrocardiogram in angina pectoris.

    British heart journal·2010
    Same journal

    Induced changes in the circulation in constrictive pericarditis.

    British heart journal·2010
    Same journal

    Angina pectoris with associated left paroxysmal ptosis.

    British heart journal·2010
    Same journal

    Myxoedema with pericardial effusion.

    British heart journal·2010
    Same journal

    Hypoxaemia tests in coronary disease.

    British heart journal·2010
    See all related articles

    Area of Science:

    • Pharmacology
    • Clinical Pharmacy
    • Patient Adherence

    Background:

    • Digoxin is a critical medication for managing heart conditions.
    • Ensuring correct digoxin dosage and patient compliance is vital for therapeutic success.

    Purpose of the Study:

    • To assess patient compliance with prescribed digoxin doses.
    • To identify the prevalence of improper digoxin intake and potential prescribing errors.
    • To evaluate long-term digoxin adherence in patients.

    Main Methods:

    • Plasma digoxin concentrations were measured on hospital admission and day 8 in 50 patients.
    • Renal function was monitored to exclude its influence on digoxin levels.
    • Long-term compliance was assessed via outpatient follow-up at 4 weeks and 3 months.

    Related Experiment Videos

    Main Results:

    • 36% of patients showed higher digoxin levels on day 8, indicating non-compliance.
    • 14% had lower levels, suggesting prior over-administration of digoxin.
    • Approximately 50% of patients exhibited improper digoxin intake.
    • 28% of patients had digoxin levels outside the therapeutic range (0.8-2.0 ng/ml).
    • Long-term follow-up revealed sustained non-compliance rates of 27% at 4 weeks and 30% at 3 months.

    Conclusions:

    • A significant proportion of patients do not adhere to their prescribed digoxin regimen.
    • Incorrect digoxin dosing and administration are prevalent, impacting treatment efficacy.
    • Communication gaps between healthcare providers and patients contribute to poor medication adherence.