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Genetic control of Rous sarcoma regression in inbred lines of chickens
Folia Biologica
|January 1, 1981
Abstract:
The fate of tumours induced by PR-RSV-C was investigated in highly inbred chicken lines congenic at the B complex, the major histocompatibility complex of the chicken. The results demonstrated that Rous sarcoma regression in congenic CB and CC lines was controlled by a gene within the B region of the chromosome. Another congenic pair of the WA and WB lines also differed in the ability to regress RSV-induced tumours and a gene within the B complex also appeared to have a significant role in the regression of Rous sarcomas.