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Cystosarcoma phyllodes.

B Schmidt, L Lantsberg, J Goldstein

    Israel Journal of Medical Sciences
    |September 1, 1981
    PubMed
    Summary
    This summary is machine-generated.

    Wide local excision for benign cystosarcoma phyllodes and mastectomy for malignant types showed a 11% recurrence and 4% mortality rate. This approach is justified, though mastectomy indications need further clarification.

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    Area of Science:

    • Oncology
    • Surgical Pathology

    Background:

    • Cystosarcoma phyllodes are rare breast tumors with unpredictable behavior.
    • Accurate diagnosis and appropriate treatment are crucial for patient outcomes.

    Purpose of the Study:

    • To evaluate the efficacy of different surgical approaches for cystosarcoma phyllodes.
    • To determine recurrence and mortality rates associated with current treatment strategies.

    Main Methods:

    • Retrospective review of 27 cystosarcoma phyllodes cases in 23 patients.
    • Treatment stratification based on histological appearance: wide local excision for benign, simple mastectomy for malignant.
    • Analysis of recurrence, metastasis, and survival data.

    Main Results:

    • Wide local excision for benign tumors resulted in a 11% local recurrence rate, all successfully treated with reexcision.

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  • Simple mastectomy for malignant tumors led to a 33% mortality rate (1/3), with the other two patients cured.
  • One case of bilateral cystosarcoma phyllodes and one associated with breast carcinoma were noted.

    • Conclusions:

    • Wide local excision for benign cystosarcoma phyllodes and mastectomy for malignant types appear to be a justified therapeutic approach.
    • The study highlights the need for further research to clarify precise indications for mastectomy in managing cystosarcoma phyllodes.