A simple computer program for calculating, modifying and drawing circular restriction maps
Related Experiment Video
Updated: Oct 14, 2026

14:14
Quantification of Strain in a Porcine Model of Skin Expansion Using Multi-View Stereo and Isogeometric Kinematics
Published on: April 16, 2017
Nucleic Acids Research
|January 11, 1982
Abstract:
An HPL program is described which constructs and draws circular restriction maps given a set of cleavage sites, together with deletion of insertion data if required. This program is of great use in the routine interpretation of restriction patterns for the analysis of recombinant DNA molecules.
Related Concept Videos
Area Computation by the Alternative Coordinate Method
The alternative coordinate method, also known as the Shoelace Formula, is a technique for determining the area of a traverse using Cartesian coordinates. This method relies on the sequential arrangement of x and y coordinates for each point of the shape, ensuring accuracy and ease of application.In this approach, each corner's x and y coordinates are listed as fractions, with the x-coordinate as the numerator and the y-coordinate as the denominator. These coordinates are arranged sequentially...
Areas Within Irregular Boundaries
Calculating areas within irregular boundaries, such as along rivers or curved roads, is crucial in various fields, including surveying, engineering, and environmental management. Surveyors often begin by creating a traverse, a connected series of straight lines approximating the area's boundary. The coordinates of each traverse point are essential for calculating the enclosed area. The double meridian distance formula is a widely used technique for this purpose. This method utilizes the...
Manipulation and Analysis
GIS manipulation and analysis functions are vital for decision-making and planning. These activities range from data retrieval tasks, such as selecting information based on specific criteria, to advanced analytical techniques that address complex spatial problems.One critical GIS analysis method is overlaying, which combines multiple data layers to examine impacts. For example, overlaying a river-dammed lake boundary with road networks can identify affected infrastructure. Another common...
Polar Curves
The spirograph is a versatile tool for visualizing the relationship between geometry and mathematical representation. In particular, it demonstrates how polar coordinates offer an alternative framework for describing curves in comparison to Cartesian coordinates. Instead of specifying a point by its horizontal and vertical displacements (x, y), polar coordinates use a radius r, the distance from the origin, and an angle θ, measured counterclockwise from the polar axis. This system is...
Level Curves and Contour Maps
Level curves and contour maps provide a way to visualize functions of two variables on a two-dimensional plane. A useful example is a topographic map, where curved lines represent locations that share the same elevation. In mathematics, these curves are called level curves or contour lines. Each contour line corresponds to points in the domain where the function has a constant value. For a function of two variables written as z = f(x,y), a level curve is defined by the equation f(x,y) = k,...
Surface Area Calculations
Surface area calculations for a graph z = f(x, y) are fundamental in engineering applications involving curved structures such as satellite dishes. A parabolic dish reflects communication signals efficiently, but engineers must determine its exact curved surface area to estimate coating materials, fabrication costs, and structural requirements. Since the rim of the dish forms a circular boundary, the surface area is calculated over a circular domain in the xy-plane.Parametric Representation of...

