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Published on: March 14, 2014
Current management of fungal enteritis
Abstract:
Fungal infections of the gastrointestinal tract have risen to higher levels of prevalence in the past decade. Major factors accounting for this increase are social changes, such as the increased ease and frequency of travel, which exposes the individual to environmental conditions that may result in fungal infection; increasing use of antibiotic and hormonal medications by otherwise healthy persons; and improved therapy for other diseases, such as polychemotherapy of cancer with its immunosuppressive effects. Both noninvasive and invasive fungal disease of the intestinal tract in otherwise healthy individuals can be successfully treated. The invasive fungal infections in patients with severe prior underlying disease are often first diagnosed postmortem, but improvement in serologic techniques now offers a possibility of earlier diagnosis and therapeutic intervention.
Insights
Gastrointestinal fungal infections are increasing due to travel, medications, and cancer therapies. Early diagnosis and treatment are possible for both healthy individuals and those with underlying conditions.
Area of Science:
- Gastroenterology
- Mycology
- Infectious Diseases
Background:
- Gastrointestinal fungal infections show increased prevalence over the last decade.
- Contributing factors include increased global travel, widespread antibiotic and hormonal medication use, and immunosuppressive cancer therapies.
- These factors create a more conducive environment for fungal proliferation in the digestive system.
Purpose of the Study:
- To review the rising prevalence of gastrointestinal fungal infections.
- To identify key factors contributing to this increase.
- To discuss current and potential diagnostic and therapeutic strategies for these infections.
Main Methods:
- Review of current literature on fungal infections of the gastrointestinal tract.
- Analysis of epidemiological trends and contributing factors.
- Evaluation of diagnostic advancements and treatment outcomes.
Main Results:
- Both noninvasive and invasive fungal infections in healthy individuals are treatable.
- Invasive infections in severely ill patients are often diagnosed postmortem.
- Advancements in serologic techniques offer potential for earlier diagnosis.
Conclusions:
- Gastrointestinal fungal infections represent a growing health concern.
- Early diagnosis and intervention are crucial for improving patient outcomes, especially in immunocompromised individuals.
- Continued research into diagnostic and therapeutic modalities is warranted.
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