Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Gestational trophoblastic neoplasia.

C B Hammond, J C Weed, D E Barnard

    CA: a Cancer Journal for Clinicians
    |November 1, 1981
    PubMed
    Summary

    Modern treatments offer a near 100% cure rate for Gestational Trophoblastic Neoplasia (GTN), a formerly high-mortality disease. Effective management combines chemotherapy, surgery, irradiation, and HCG monitoring for patient survival and future pregnancies.

    Related Concept Videos

    You might also read

    Related Articles

    Articles linked to this work by shared authors, journal, and citation graph.

    Sort by
    Same author

    Progesterone therapy of uterine fibromyomata.

    The Journal of clinical endocrinology and metabolism·2010
    Same author

    True hermaphroditism; report of a case with an ovotestis, and endocrine studies.

    The Journal of clinical endocrinology and metabolism·2010
    Same author

    The effect of prolapse of the ovaries upon cystic degeneration and ovulation.

    Western journal of surgery, obstetrics, and gynecology·2010
    Same author

    True hermaphroditism; endocrine studies in a case of ovotestis.

    The Journal of clinical endocrinology and metabolism·2010
    Same author

    Progesterone therapy of uterine fibromyomas.

    The Journal of clinical endocrinology and metabolism·2010
    Same author

    False positive hCG.

    Obstetrics and gynecology·2001

    Area of Science:

    • Gynecology
    • Oncology
    • Reproductive Medicine

    Background:

    • Gestational Trophoblastic Neoplasia (GTN) historically presented a significant mortality risk.
    • Advancements in medical technology have dramatically improved patient outcomes.

    Purpose of the Study:

    • To highlight the high curability of GTN with contemporary methods.
    • To emphasize the integrated approach required for successful GTN treatment.

    Main Methods:

    • Multimodal therapy including chemotherapy, surgery, and irradiation.
    • Utilizing the human chorionic gonadotropin (HCG) assay for disease monitoring.
    • Supportive care protocols.

    Main Results:

    • Near 100% cure rates achieved for patients with GTN.
    • Significant reduction in the historically high death rate associated with GTN.
    • Successful future pregnancies are possible for survivors.

    Conclusions:

    • Modern diagnostic and therapeutic strategies have transformed GTN from a high-mortality disease to a curable condition.
    • A comprehensive treatment approach integrating chemotherapy, surgery, irradiation, and HCG monitoring is crucial for optimal patient survival.
    • The successful management of GTN allows for a high likelihood of survival and the potential for future successful pregnancies.

    Related Experiment Videos