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[Colonic involvement in systemic mastocytosis (author's transl)]
La Semaine Des Hopitaux : Organe Fonde Par L'Association D'Enseignement Medical Des Hopitaux De Paris
|June 10, 1982
Summary
Systemic mastocytosis commonly affects the stomach and small intestine. This case highlights diffuse colonic involvement, potentially explaining diarrhea in affected patients.
Area of Science:
- Gastroenterology
- Oncology
- Radiology
Background:
- Systemic mastocytosis (SM) frequently involves the gastrointestinal tract, typically manifesting as gastric, duodenal, or small bowel lesions.
- Colonic involvement in SM is considered rare, though its prevalence may be underestimated.
Purpose of the Study:
- To report a case of diffuse colonic involvement in systemic mastocytosis.
- To correlate radiological findings with endoscopic and histological data.
- To discuss the potential role of colonic involvement in SM-associated diarrhea.
Main Methods:
- A case study involving a patient with systemic mastocytosis.
- Diagnosis of colonic involvement using double contrast barium enema (radiological examination).
- Correlation of radiological findings with endoscopic and histological examinations.
Main Results:
- Radiological examination revealed diffuse colonic involvement.
- Findings were attributed to submucosal edema and a polymorphic cellular infiltrate.
- Endoscopic and histological examinations confirmed the submucosal infiltration.
Conclusions:
- Diffuse colonic involvement can occur in systemic mastocytosis.
- This involvement, characterized by submucosal edema and cellular infiltrate, may be more common than previously recognized.
- Colonic manifestations could be a significant factor contributing to diarrhea in patients with systemic mastocytosis.