Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Search research articles

Related Experiment Videos

Sympathoadrenal reactivity in exercise-induced asthma.

K Larsson, P Hjemdahl, A Martinsson

|November 1, 1982

Summary

Sympathoadrenal activity is not altered in asthma patients. Exercise did not cause different catecholamine responses between exercise-induced asthma (EIA) and non-exercise-induced asthma (NEIA) patients.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Children developing type 1 diabetes before 6 years of age have increased linear growth independent of HLA genotypes.

Diabetologia·2008

Same author

Effect of coadsorbed dopants on diamond initial growth processes: CH3 adsorption.

The journal of physical chemistry. A·2008

Same author

Treatment of exercise-induced asthma, respiratory and allergic disorders in sports and the relationship to doping: Part II of the report from the Joint Task Force of European Respiratory Society (ERS) and European Academy of Allergy and Clinical Immunology (EAACI) in cooperation with GA(2)LEN.

Allergy·2008

Same author

A time-of-flight-Mott apparatus for soft x-ray spin resolved photoemission on solid samples.

The Review of scientific instruments·2008

Same author

Exercise-induced asthma, respiratory and allergic disorders in elite athletes: epidemiology, mechanisms and diagnosis: part I of the report from the Joint Task Force of the European Respiratory Society (ERS) and the European Academy of Allergy and Clinical Immunology (EAACI) in cooperation with GA2LEN.

Allergy·2008

Same author

Fluticasone and ibuprofen do not add to the effect of salmeterol on organic dust-induced airway inflammation and bronchial hyper-responsiveness.

Journal of internal medicine·2008

Area of Science:

Pulmonary Medicine
Cardiovascular Physiology
Endocrinology

Background:

Asthma, particularly exercise-induced asthma (EIA), may involve altered sympathoadrenal activity.
Previous studies suggested exaggerated catecholamine responses contribute to post-exercise bronchoconstriction in EIA.

Purpose of the Study:

To investigate sympathoadrenal activity during exercise in patients with EIA, non-exercise-induced asthma (NEIA), and healthy controls.
To determine if catecholamine response to exercise differs between asthma phenotypes and influences post-exercise airway function.

Main Methods:

Eight EIA patients, eight NEIA patients, and eight healthy controls underwent orthostatic and standardized exercise tests.
Measurements included plasma catecholamine levels, plasma cAMP, FEV1 (forced expiratory volume in 1 second), and Sgaw (specific airway conductance).
Participants abstained from medication for at least one week prior to testing.

Main Results:

Exercise induced bronchoconstriction (decreased FEV1) in EIA patients and less pronounced bronchoconstriction (decreased Sgaw) in NEIA patients.
Basal and exercise-induced plasma catecholamine (noradrenaline and adrenaline) levels were similar across all groups.
Plasma cAMP levels increased with exercise, and an inverse correlation was observed between cAMP increase and Sgaw decrease in EIA patients.

Conclusions:

The study does not support the hypothesis that exaggerated catecholamine responses to exercise cause post-exercise bronchoconstriction in EIA via alpha-adrenoceptor stimulation.
Observed differences in previous studies may be attributable to methodological variations.
Sympathoadrenal activity response to exercise appears similar in EIA, NEIA, and healthy individuals.

Related Experiment Videos