[Reye's syndrome: pathological aspects]

Area of Science:

• Pediatrics
• Neurology
• Pathology

Background:

• Reye's syndrome is a rare but serious condition affecting children and teenagers.
• It is characterized by acute liver and brain swelling.

Observation:

• A 7-month-old infant presented with digestive issues, hepatomegaly, seizures, rash, hypoglycemia, and high blood urea.
• Clinical symptoms were associated with post-mortem findings.

Findings:

• Post-mortem examination revealed diffuse liver steatosis, renal tubuli steatosis, myocardial fiber steatosis, meningoencephalic edema, and viral pneumonia.
• These clinico-pathologic features confirmed the diagnosis of Reye's syndrome.

Implications:

• This case highlights the diagnostic challenges of Reye's syndrome, particularly in regions with limited reported cases.
• Emphasizes the importance of recognizing the syndrome's diverse clinical and pathological manifestations.