Radioallergosorbent testing with p-tolyl monoisocyanate in toluene diisocyanate workers

Sera from 149 occupationally exposed toluene diisocyanate (TDI) workers were tested by RAST with p-tolyl monoisocyanate human serum albumin (TMI-HSA). Of the seven positives, one had a history suggestive of TDI asthma and one had a rash which may have been TDI related. These results indicate that false positive RAST with TMI-HSA may occur in asymptomatic workers.