Normal Hoffmann reflex latencies (H-M interval) in relation to age and body length

Area of Science:

• Neurology
• Human Physiology

Background:

• The Hoffmann reflex (H-M interval) is a neurophysiological measure.
• Standard H-M interval values may not apply universally across diverse age and body length demographics.

Purpose of the Study:

• To investigate the impact of age and body length on the H-M interval.
• To establish more accurate normative ranges for H-M interval and its asymmetry.

Main Methods:

• Tested 179 healthy subjects aged 15-75 years and measuring 150-200 cm.
• Analyzed H-M interval and asymmetry data in relation to age and body length.

Main Results:

• Normal upper limits for the H-M interval vary widely, from 22.0 ms to 34.3 ms based on sex, age, and height.
• A previously cited limit of 28 ms is only valid for younger adults under 175 cm.
• A normal asymmetry limit of less than 3 ms is more appropriate for mixed populations than the commonly used 2 ms.

Conclusions:

• Current standard H-M interval limits require adjustment for age and body length.
• Revised normative data for H-M interval and asymmetry improve diagnostic accuracy in clinical neurology.
• A 3 ms threshold for H-M interval asymmetry is recommended for broader applicability.