[Cytoplasmic channel-forming factor of rat liver]

A component capable of modifying bilayer phospholipid membranes (BPM) with the formation of conductivity channels was found in the fraction cytoplasmic proteins of the rat liver. Cation-anionic selectivity of channels depending on medium pH and cation type was studied. Current voltage characteristics of single channel is extremely asymmetric. It is suggested that the studied factor is a cytoplasmic regulator of the permeability of membrane structure in the cell.