Related Experiment Video

Updated: Aug 6, 2026

Contribution of the Na+/K+ Pump to Rhythmic Bursting, Explored with Modeling and Dynamic Clamp Analyses
08:34

Contribution of the Na+/K+ Pump to Rhythmic Bursting, Explored with Modeling and Dynamic Clamp Analyses

Published on: May 9, 2021

[Kinetic model of the gating system of the sodium channel in a Ranvier node membrane]

A V Lonskiĭ, A A Perk, N G Roshchina

    Tsitologiia
    |November 1, 1983
    PubMed

    More Related Videos

    Computational Modeling of Retinal Neurons for Visual Prosthesis Research - Fundamental Approaches10:50

    Computational Modeling of Retinal Neurons for Visual Prosthesis Research - Fundamental Approaches

    Published on: June 21, 2022

    Dynamic Clamp Methods to Investigate Impaired Neuronal Excitability Associated with Autism08:44

    Dynamic Clamp Methods to Investigate Impaired Neuronal Excitability Associated with Autism

    Published on: October 17, 2025

    Related Concept Videos

    Non-gated Ion Channels01:24

    Non-gated Ion Channels

    Ion channels are specialized proteins on the plasma membrane that allow charged ions to pass down their electrochemical gradient. Their main function is to maintain the membrane potential which is critical for cell viability. These channels are either gated or non-gated and can transport more than a thousand ions within milliseconds for the cellular event to occur.
    Compared to the gated ion channels, the non-gated channels, also known as leakage or passive channels, have no gating mechanism.
    The Role of Ion Channels in Neuronal Computation01:19

    The Role of Ion Channels in Neuronal Computation

    A postsynaptic neuron usually receives numerous impulses from several other presynaptic neurons. The axon hillock of the postsynaptic neuron integrates all these signals and determines the likelihood of firing an action potential.
    Sometimes a single EPSP is strong enough to induce an action potential in the postsynaptic neuron. However, multiple presynaptic inputs must often create EPSPs around the same time for the postsynaptic neuron to be sufficiently depolarized to fire an action potential.
    Voltage-gated Ion Channels01:26

    Voltage-gated Ion Channels

    Voltage-gated ion channels are transmembrane proteins that open and close in response to changes in the membrane potential. They are present on the membranes of all electrically excitable cells such as neurons, heart, and muscle cells.
    Generally, all voltage-gated ion channels have a 'voltage-sensing domain' that spans the lipid bilayer. The charged residues in the sensor move in response to the membrane potential changes that open the channel allowing ions movement. There are several types of...
    Non-gated Ion Channels01:24

    Non-gated Ion Channels

    Ion channels are specialized proteins on the plasma membrane that allow charged ions to pass down their electrochemical gradient. Their main function is to maintain the membrane potential which is critical for cell viability. These channels are either gated or non-gated and can transport more than a thousand ions within milliseconds for the cellular event to occur.
    Compared to the gated ion channels, the non-gated channels, also known as leakage or passive channels, have no gating mechanism.
    Ligand-Gated Ion Channel Receptor: Gating Mechanism01:30

    Ligand-Gated Ion Channel Receptor: Gating Mechanism

    Ligand-gated ion channels are transmembrane proteins that play a vital role in intercellular communication and functions of the nervous system. They allow the influx of ions across the membrane once the neurotransmitter binds, allowing the subsequent transmission of electrical excitation across the neurons. Other ligand-gated ion channels, like the γ-aminobutyric acid (GABA) receptor, permit anions like chloride into the cells on the binding of the GABA molecule. Their entry into the cell...
    Voltage-gated Ion Channels01:26

    Voltage-gated Ion Channels

    Voltage-gated ion channels are transmembrane proteins that open and close in response to changes in the membrane potential. They are present on the membranes of all electrically excitable cells such as neurons, heart, and muscle cells.
    Generally, all voltage-gated ion channels have a 'voltage-sensing domain' that spans the lipid bilayer. The charged residues in the sensor move in response to the membrane potential changes that open the channel allowing ions movement. There are several types of...